"I glanced around at the books upon my shelves. Often enough, following some outrage by the brilliant Chinese doctor whose genius was directed to the discovery of new and unique death agents, we had obtained a clue in those works of a scientific nature which bulk largely in the library of a medical man. There are creatures, there are drugs, which, ordinarily innocuous, may be so employed as to become inimical to human life; and in the distorting of nature, in the disturbing of balances and the diverting of beneficent forces into strange and dangerous channels, Dr. Fu-Manchu excelled. I had known him to enlarge, by artificial culture, a minute species of fungus so as to render it a powerful agent capable of attacking man; his knowledge of venomous insects has probably never been paralleled in the history of the world; whilst, in the sphere of pure toxicology, he had, and has, no rival; the Borgias were children by comparison. But, look where I would, think how I might, no adequate explanation of this latest outrage seemed possible along normal lines."
Chapter 14, The Return of Dr. Fj-Manchu, Sax Rohmer
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